N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam

Details N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam

1990-04-11

1991-08-27

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 69, A61K 3148, C07D45706

Patent

active

050433415

ABSTRACT:
This invention provides N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides useful for blocking 5HT.sub.2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.

REFERENCES:
patent: 4931447 (1990-06-01), Foreman et al.
Berde et al., Ergot Alkoloids and Related Compounds 1978, pp. 35, 323-324.

Affiliated with

Also associated with

Rating

N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxam will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1414308