N-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]-1H-benzimidazole-1-butana

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548333, A61K 31415, C07D23506

Patent

active

045173109

ABSTRACT:
The compound N-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]-1H-benzimidazole-1-butanamine and methods for its manufacture and use are described herein. The compound is a cardiotonic agent useful primarily in the treatment of congestive heart failure.

REFERENCES:
patent: 3905990 (1975-09-01), Ehrmann et al.
Evans, D., et al., Pharmac. Ther. 16, 303 (1982).
Sonnenblick, E., et al., New Eng. J. Med., 300 (1), 17 (1979).

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