N-[2-amino-4-substituted[[(pyrrollo or pyrido)[2,3-d]pyrimidinyl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

544280, A61K 31505, C07D47104, C07D47504, C07D47508

Patent

active

051964244

ABSTRACT:
This invention relates to N-[2-amino-4-substituted-[[(pyrrolo or pyrido) [2,3-d]pyrimidinyl]-alkyl]benzoyl]-L-glutamic acid compounds, intermediates for their synthesis, pharmaceutical formulations containing those compounds, and their use as antineoplastic agents.

REFERENCES:
patent: 4595530 (1986-06-01), Nishimura et al.
patent: 4684653 (1987-08-01), Taylor et al.
patent: 4882333 (1989-11-01), Shih et al.
patent: 4902796 (1990-02-01), Taylor et al.
patent: 4921858 (1990-05-01), Malone et al.
patent: 4923872 (1990-05-01), Kostlan et al.
patent: 4927828 (1990-05-01), Taylor et al.
patent: 4976206 (1991-02-01), Taylor et al.
patent: 4988702 (1991-01-01), Kostlan et al.
patent: 4988813 (1991-01-01), Taylor et al.
patent: 5026851 (1991-06-01), Taylor et al.
Taylor, et al., J. Med. Chem., 28, 914-921 (1985).
Seela, et al., Liebigs Ann. Chem., 15-19 (1987).
Bernetti, et al., J. Org. Chem., 27, 2863-2865 (1962).
Temple, et al., J. Org. Chem., 47, 761-763 (1982).
Taylor, et al., J. Org. Chem., 48, 4852-4860 (1983).

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