N-2[(4-fluoro-phenyl)-1-methyl]-2-ethyl-N-methyl-N-propynyl amin

Details N-2[(4-fluoro-phenyl)-1-methyl]-2-ethyl-N-methyl-N-propynyl amin N-2[(4-fluoro-phenyl)-1-methyl]-2-ethyl-N-methyl-N-propynyl amin

1989-02-15

1990-10-02

Hines, Robert V.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

564374, 564375, 564376, 564377, 564381, 564304, A61K 31135, C07C 8728

Patent

active

049607979

ABSTRACT:
The invention relates to the new N-[2-/4-fluorophenyl/-1-methyl]-ethyl-N-methyl-N-propynyl amine of the Formula I ##STR1## and isomers and salts thereof. The compound of the formula I is useful as a selective MAO inhibitor.

REFERENCES:
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patent: 3496195 (1970-02-01), Ecsery et al.
patent: 4105695 (1978-08-01), Partyka et al.
patent: 4156017 (1979-05-01), Kruger et al.
patent: 4314081 (1982-02-01), Molloy et al.
patent: 4835315 (1989-05-01), Lafon
Wolff, "Burger Medicinal Chemistry", Part III, 4th Ed., pp. 1014-1015, (1979).
Knoll et al., "Arch. Int. Pharmacodyn.", vol. 155, pp. 154-163 (1965).
Saunders, "The Aromatic Diazo Compounds", pp. 283-284 (1945).
Goodman & Gilman. The Pharmacological Basis of Therapeutics, Fifth Edition (1975), pp. 18-183.

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