N-(1-Substituted-3-pyrrolidinyl)benzamides

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424274, C07D20714, A61K 3140

Patent

active

042798221

ABSTRACT:
N-(1-Substituted-3-pyrrolidinyl)benzamides of the formula ##STR1## wherein R is cycloalkyl or phenyllower-alkyl; R.sup.1 is hydrogen or lower alkyl of 1 to 8 carbon atoms; R.sup.2 is acetamido, amino, methylamino, dimethylamino, benzyloxy, halogen, lower alkoxy, methylmercapto, nitro, cyano, hydroxy, sulfamoyl, bis(methylsulfonyl)amino, methylsulfonylamino, aminomethyl or acetylaminomethyl and can be the same or different; n is an integer from one to three inclusive with the proviso that when R.sup.2 is amino, nitro, halogen or lower alkoxy, n is greater than one, and pharmaceutically acceptable acid addition salts thereof are disclosed.

REFERENCES:
patent: 3342826 (1967-09-01), Miller et al.
patent: 3577440 (1971-05-01), Lunsford et al.
patent: 4002757 (1977-01-01), Cale, Jr.
patent: 4013670 (1977-03-01), Banitt et al.

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