N-(1-substituted-3-pyrrolidinyl)-4-quinolinecarboxamides

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260287R, 2603268, 424274, A61K 3147

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active

040027570

ABSTRACT:
Novel N-(1-substituted-3-pyrrolidinyl)-1-naphthalene and 4-quinolinecarboxamides of the formula: ##STR1## wherein R is lower cycloalkyl, R.sup.1 is hydrogen, lower alkyl or aryl, R.sup.2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, R.sup.3 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, Y is carbon or nitrogen and pharmaceutically acceptable acid addition salts thereof having anti-emetic properties are disclosed.

REFERENCES:
patent: 3133061 (1964-05-01), Kirchner
Chem. Abs., 1973, vol. 78, p. 84191j.
Chem. Abs., 1973, vol. 78, p. 111082h.

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