N-(1-substituted-3-pyrrolidinyl)-4-quinoline carboxamides

Details N-(1-substituted-3-pyrrolidinyl)-4-quinoline carboxamides N-(1-substituted-3-pyrrolidinyl)-4-quinoline carboxamides

1976-05-05

1978-05-02

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424258, C07D40112

Patent

active

040874281

ABSTRACT:
Novel N-(1-substituted-3-pyrrolidinyl)-1-naphthalene- and 4-quinolinecarboxamides of the formula: ##STR1## wherein R is lower cycloalkyl, R.sup.1 is hydrogen, lower alkyl or aryl, R.sup.2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, R.sup.3 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, Y is carbon or nitrogen and pharmaceutically acceptable acid addition salts thereof having anti-emetic properties are disclosed.

REFERENCES:
patent: 1825623 (1931-09-01), Miescher
patent: 3829434 (1974-08-01), Evanega et al.

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