N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides

Details N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides

1976-05-05

1978-02-14

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260286R, 260287F, 26032647, 424258, 424274, C07D20714, A61K 3140, A61K 3147, C07D40112

Patent

active

040737969

ABSTRACT:
Novel N-(1-substituted-3-pyrrolidinyl)-1-naphthalene- and 4-quinolinecarboxamides of the formula: ##STR1## wherein R is lower cycloalkyl, R.sup.1 is hydrogen, lower alkyl or aryl, R.sup.2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, R.sup.3 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, Y is carbon or nitrogen and pharmaceutically acceptable acid addition salts thereof having anti-emetic properties are disclosed.

REFERENCES:
patent: 3342826 (1967-09-01), Miller et al.
patent: 3577440 (1971-05-01), Lunsford et al.
patent: 4002757 (1977-01-01), Cale, Jr.
Foldeak et al.; Chem. Abs., vol. 59:560g-561b, (1962).
Giannini:Chem. Abs., vol. 75:20222a, (1971).

Affiliated with

Also associated with

Rating

N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-(1-substituted-3-pyrrolidinyl)-1-naphthalene carboxamides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-524100