N-(1-(1,3-D ihydro-1,3-dioxo-2H-benz(de)-isoquinolin-2-yl)alkyl)

Details N-(1-(1,3-D ihydro-1,3-dioxo-2H-benz(de)-isoquinolin-2-yl)alkyl) N-(1-(1,3-D ihydro-1,3-dioxo-2H-benz(de)-isoquinolin-2-yl)alkyl)

1975-01-06

1976-05-25

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260281S, 424258, C07D40106

Patent

active

039592863

ABSTRACT:
Compounds of the following formula and their acid addition salts ##SPC1##
Wherein R.sup.1 and R.sup.2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; R.sup.3 is phenyl or substituted phenyl; and R is lower alkyl or cycloalkyl of 3 to 7 carbons are disclosed. These compounds exhibit antidepressant activity. In addition these compounds are useful as antiinflammatory agents.

REFERENCES:
patent: 3247208 (1966-04-01), Schenker
patent: 3625947 (1971-12-01), Noguchi

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