Myoinositol derivatives and preparation process thereof

Details Myoinositol derivatives and preparation process thereof Myoinositol derivatives and preparation process thereof

1992-09-24

1994-03-08

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558161, C07F 9117

Patent

active

052929132

ABSTRACT:
Disclosed herein are phosphoric acid esters of myoinositol, which are represented by the following general formula (I): ##STR1## and their salts, as well as a preparation process thereof. The myoinositol derivatives can each be obtained by causing a phosphorylating agent to act on a myoinositol derivative substituted with catalytic reduction removable substituent groups at the positions other than those desired to be substituted by phosphoric acid residual groups and then catalytically reducing the thus-phosphorylated myoinositol.

REFERENCES:
patent: 4474806 (1984-02-01), Beattie
patent: 4515722 (1985-07-01), Yang
Krylova, V. N. et al. Chemical Abstracts 93, 95518g (1980).
Kosolapoff, G. M., et al. Organic Phosphorus Compounds; John Wiley and Sons; New York, 1973; pp. 229-230.
Tetrahedron Letters, vol. 27, No. 27, 1986, pp. 3157-3160, Pergamon Press, Oxford, GB; S. Ozaki et al. "Total synthesis of optically active myo-insitol 1,4,5-tris(phosphate)".

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