Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood
Reexamination Certificate
2011-07-12
2011-07-12
Wallenhorst, Maureen M (Department: 1777)
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
C436S063000, C436S086000
Reexamination Certificate
active
07977105
ABSTRACT:
Disclosed is a method for diagnosing myocardial infarction in a subject who suffers from acute coronary syndrome and has a cardiac troponin level, which is detectable, but lower than the level that is considered as being indicative for a myocardial infarction. Also disclosed is a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from acute coronary syndrome and has a cardiac troponin level which is detectable, but lower than a level that is considered as being indicative for a myocardial infarction. These methods are based on the determination of myoglobin and, optionally, Heart-type fatty acid binding protein (H-FABP) in a sample of the subject and comparing the amount of myoglobin and, optionally, H-FABP to reference amounts. Also disclosed are kits or devices to carry out the methods.
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Hess Georg
Huedig Hendrik
Kientsch-Engel Rosemarie
Zdunek Dietmar
Roche Diagnostics Operations Inc.
Wallenhorst Maureen M
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