Myeloid cell promoter and constructs containing same

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S023100

Reexamination Certificate

active

06881834

ABSTRACT:
The present invention provides novel myeloid cell specific promoters, and cis-acting elements that influence the activity of a myeloid cell specific promoters, as well as promoter-heterologous gene constructs and transfected myeloid cells which include the novel promoters and/or the novel cis-acting elements. The present invention also provides a method of transfecting myeloid cells and a method of producing a selected product within the transfected cells. The invention also includes a method for identifying factors that can regulate myeloid cell specific transcription.

REFERENCES:
patent: 5502176 (1996-03-01), Tenen et al.
patent: 5556954 (1996-09-01), Burn et al.
J. Noti et al., Human p150,95 α-Subunit: Genomic Organization and Analysis of the 5′-Flanking Region.DNA and Cell Biol., vol. 11, pp. 123-138 (1992).
A. Back et al., Leukocyte Integrin CD11b Promoter Directs Expression in Lymphocytes and Granulocytes in Transgenic Mice.Blood, vol. 5, No. 4, pp. 1017-1024 (1995).
K. Ritchie et al., The Human Leukocyte Integrin CD11a Promoter Directs Expression in Leukocytes of Transgenic Mice.Blood, vol. 85, No. 1, pp. 147-155 (1995).
M. Van der Vieren et al., A Novel Leukointegrin, αdβ2, Binds Preferentially to ICAM-3.Immunity, vol. 3, pp. 683-690 (1995).
D. Wong et al., Cloning and Chromosomal Localization of a Novel Gene-Encoding a Human β2-Integrin α Subunit.Gene, vol. 171, pp. 291-294 (1996).
T. Brocker et al., Targeted Expression of Major Histocompatibility Complex (MHC) Class II Molecules Demonstrates that Dendritic Cells Can Induce Negative but Not Positive Selection of Thymocytes In Vivo.J. Exp. Med., vol. 185, No. 3, pp. 541-550 (1997).
C. S. Shelley et al., Mapping of the Human CD11c (ITGAX) and CD11d (ITGAD) Genes Demonstrates that they are Arranged in Tandem Separated by No More Than 11.5 kb.Genomics, vol. 49, pp. 334-336 (1998).
K. Garber, Waiting for Cancer Vaccines.Mod. Drug Discovery, pp. 37-44 (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Myeloid cell promoter and constructs containing same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Myeloid cell promoter and constructs containing same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Myeloid cell promoter and constructs containing same will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3369634

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.