Myeloid cell leukemia associated gene MCL-1

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435 6, 435 723, 4353201, 4352351, 4351723, 5303877, 5303888, 536 235, 536 231, 935 6, 935 32, 935 34, 935 55, 935 57, 935 70, 935 71, 424450, C07H 2100

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058888128

ABSTRACT:
A gene, mcl-1, of the bcl-2 family is disclosed along with its nucleotide and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of utilizing the mcl-1 nucleotide and polypeptide sequences.

REFERENCES:
Kozopas et al. P.N.A.S. Apr. 1993. vol. 90:3516-3520.
Okubo et al. Nature Genetics. Nov. 1992. vol. 2:173-179.

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