Mycobacterium tuberculosis specific DNA fragment

Details Mycobacterium tuberculosis specific DNA fragment Mycobacterium tuberculosis specific DNA fragment

1997-12-24

2000-09-05

Swartz, Rodney P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4241681, 4242481, 4352531, 536 237, 536 243, 536 2432, C07H 2102, C07H 2104, A61K 3940, C12N 112

Patent

active

061145149

ABSTRACT:
This invention relates to a Mycobacterium tuberculosis specific DNA fragment containing IS like and repetitive sequences, a method of production of such DNA fragment and the use of such DNA fragment, for example, to rapidly diagnose Mycobacterium tuberculosis infection in clinical samples, and to identify clinical isolates of Mycobacterium tuberculosis. The DNA fragment may be used to determine information about the epidemiology of Mycobacterium tuberculosis infection.

REFERENCES:
patent: 5370998 (1994-12-01), Crawford et al.
Kiehn, T.E., Clinical Infectious Diseases, 17 (Supp 2), 1:S447-S454, (1993) .

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