Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2007-09-04
2009-10-13
Swartz, Rodney P. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S184100, C424S185100, C424S243100, C530S300000, C530S350000, C536S023100, C536S023700
Reexamination Certificate
active
07601358
ABSTRACT:
Mycobacterium tuberculosisproteins and protein compositions that are components of a desaturase complex are provided. TheMycobacterium tuberculosisdesaturase complex may include a desaturase and an oxidoreductase. The complex may include the rv3229c and rv3230c gene products ofMycobacterium tuberculosis. Vectors for expressing the desaturase and the oxidoreductase can be packaged together, including a label that indicates their use as a complex for analyzing desaturation of fatty acids. In addition, methods for screening target ligands specific for a desaturase complex are also provided.
REFERENCES:
patent: 2005/0180963 (2005-08-01), Adams et al.
Ausubel et al.,Current Protocols in Molecular Biology, vols. 1-4, John Wiley & Sons, Inc., New York, NY (1987-2004).
Bateman et al., “The Pfam protein families datebase,”Nucl. Acids Res., 32: D138-D141 (2004).
Dieffenbach et al.,PCR Primer: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1995).
Falvella et al., “Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats,”Carcinog. 23(11):1922-1936 (2002).
Kriegler,Gene Transfer and Expression: A Laboratory Manual, Stockton Press, New York, NY (1990).
Lu et al., “Gene Expression Changes Associated With Chemically Induced Rated Mammary Carcinogenesis,”J. Mol. Carcinog., 20:204-215 (1997).
Miyaji et al., “Expression of Human Lymphotoxin Derivatives inEscherichia coliand Comparison of Their Biological Activity in Vitro,”Agric. Biol. Chem., 53(1):277-279 (1989).
Ntambi et al., “Regulation of stearoyl-CoA desaturases and role in metabolism,”Prog. Lipid. Res., 43:91-104 (2003).
Pala et al., “Erythrocyte Membrane Fatty Acids and Subsequent Breast Cancer: a Prospective Italian Study,”J. Nat. Canc. Inst., 93(14):1088-1095 (2001).
Sambrook et al., 2000,Molecular Cloning: A Laboratory Manual, third edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Sambrook et al., 1989,Molecular Cloning: A Laboratory Manual, second edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Sekine et al., Cloning and expression of cDNA for salmon growth hormone inEscherichia coli, Proc. Natl. Acad. Sci. USA., 82:4306-4310 (1985).
Yanisch-Perron et al., “Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors,”Gene, 33:103-119 (1985).
Whitney et al., “Functional characterisation of two cytochromeb5-fusion desaturases fromAnemone leveillei: the unexpected identification of a fatty acid Δ6-desaturase,”Planta, 217:987-992 (2003).
International Search Report dated Sep. 23, 2008 for PCT Application No. PCT/US07/77423.
Chang Yong
Fox Brian G.
Brinks Hofer Gilson & Lione
Swartz Rodney P.
Wisconsin Alumni Research Foundation
LandOfFree
Mycobacterium tuberculosis protein composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mycobacterium tuberculosis protein composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mycobacterium tuberculosis protein composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4117302