Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1980-09-08
1982-05-04
Tanenholtz, Alvin E.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435865, C12N 120
Patent
active
043283152
ABSTRACT:
Mutants which are used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione (AD). ADD and AD are valuable intermediates to make useful steroids.
REFERENCES:
Lamanna et al., Basic Bacteriology, 3rd Ed., The Williams and Wilkins Co., pp. 723-727 (1965).
Metzler, Biochemistry, Academic Press Inc., pp. 945 & 946 (1977).
Mamoli et al. Ber. 70, pp. 470 & 2079 (1937).
Biggs Candice B.
Pyke Thomas R.
Wovcha Merle G.
Saliwanchik Roman
Tanenholtz Alvin E.
The Upjohn Company
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