Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1980-08-08
1982-08-17
Tanenholtz, Alvin E.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435865, C12P 3316, C12N 120
Patent
active
043450342
ABSTRACT:
Mutant which is used in a novel microbiological process to selectively transform steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield androst-4-ene-3,17-dione (AD) as essentially the sole transformed product. AD is a valuable intermediate to make useful steroids.
REFERENCES:
Lamanna et al., Basic Bacteriology, The Williams & Wilkins Co., pp. 722-727 (1965).
Metzler, Biochemistry, Academic Press Inc., pp. 945 & 946 (1977).
Mamoli et al., Ber. 70, pp. 470 & 471, 2079-2082 (1937).
Brooks Kevin E.
Wovcha Merle G.
Saliwanchik Roman
Tanenholtz Alvin E.
The Upjohn Company
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