Mycobacterium fortuitum mutant

Details Mycobacterium fortuitum mutant Mycobacterium fortuitum mutant

1980-09-08

1982-08-17

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435172, 435865, C12N 120

Patent

active

043450334

ABSTRACT:
Mutant which is used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield predominantly androst-4-ene-3,17-dione (AD) and small amounts of androsta-1,4-diene-3,17-dione (ADD). AD is a valuable intermediate to make useful steroids.

REFERENCES:
Lamanna et al., Basic Bacteriology, The Williams & Wilkins Co., pp. 722-727 (1965).
Metzler, Biochemistry, Academic Press Inc., pp. 945 & 946 (1977).
Mamoli et al., Ber. 70, 470, 2079 (1937).

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