Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2005-02-22
2005-02-22
Swartz, Rodney P (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S130100, C424S164100, C424S168100, C424S184100, C424S200100, C424S234100, C435S001200, C435S004000, C435S007100, C435S007400, C435S029000, C435S183000, C435S193000, C435S440000, C435S471000
Reexamination Certificate
active
06858213
ABSTRACT:
Novel mycobacterial sulfation pathway enzymes and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting growth and/or virulence of a pathogenicmycobacterium, and methods of treating disease conditions associated with a pathogenicmycobacterium, particularly by administering an inhibitor of a mycobacterial sulfation pathway enzyme.
REFERENCES:
patent: 6046002 (2000-04-01), Davis et al.
Gavel et al., ATP Sulfurylases from Sulfate-Reducing Bacteria of the Genus Desulfovibrio. A Novel Metalloprotein Containing Cobalt and Zinc. Biochemistry Oct. 26 1998, vol. 37, pp. 16225-16232.
Abola et al. Reduction of Adenosine-5' Phosphosulfate Instead of 3' Phosphoadenosine-5' Phosphosulfate in Cyteine Biosynthesis by Rhizobium Meliloti and other Members of the Family Rhizobiaceae, S. Bacteriology vol. 181 No. 17 p. 5280-5287 1999.
Bloom, et al.Science, (1999) vol. 257: 105-1064.
Bronzna, et al.Infect Immun., (1991) vol. 59: 2542-2548.
Cole, et al.Nature, (1998) vol. 393: 537-544.
Daffe, et al.Adv. Microb. Physiol., (1998) vol. 39: 149-152.
Goren, et al.Proc. Natl. Acad. Sci. USA, (1976) vol. 73: 2510-2514.
Hemmerich, et al.Glycobiol., (2000) vol. 10: 848-856.
Khoo, et al.J. Biol Chem., (1999) vol. 274: 9778-9785.
Lopez Marin, et al.Biochem., (1992) vol. 31: 11106-11111.
Pabst, et al.J. Immunol., (1988) vol. 140: 634-640.
Tsukamara, et al.Microbiol. Immunol., (1981) vol. 25: 215.
Zhang, et al.Immunol., (1991) vol. 146: 2730-2736.
Bertozzi Carolyn R.
Mougous Joseph D.
Williams Spencer J.
Borden Paula A.
Bozicevic Field & Francis LLP
Swartz Rodney P
The Regents of the University of California
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