Mycobacterial secretory expression vectors and transformants

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4242001, 435 691, 435 693, 435 697, 4352523, C12N 121, C12N 1574, C12P 2100, C12P 2102

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active

060156961

ABSTRACT:
A secretory vector expressed in mycobacteria comprising a promoter, a signal sequence having ligated therewith a DNA nucleotide sequence encoding heterologous polypeptide and replicator region capable of replication in mycobacteria is disclosed. A transformant that has been transformed with the secretory vector, as well as a vaccine comprising the transformant is provided.

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