Mycobacterial nucleic acid hybridization probes and methods of u

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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4353201, 536 231, 536 243, 536 2432, 536 2532, C12N 1500, C07H 2102, C07H 2104, C07H 2100

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058374558

ABSTRACT:
Fragments of nucleic acids derived from an appropriate mycobacteria genome, particularly Mycobacterium tuberculosis, their applications in the diagnosis of mycobacteria infections, as well as plasmides containing said fragments. The nucleotidic sequence is comprised of a nucleotidic sequence repeated in the genome of a mycobacterium and specific of the bacillus of tuberculosis and is characterized by a strong hybridation with M. tuberculosis.

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Eisenach et al. (1988) J. Clin. Microbiol. 26:2240-45.
Eisenach et al. (1986) Am. Review Respir. Dis. 133:1065-68.
Thierry et al. (1990) Nucl. Acids Res. 18:188.
Matthews et al. (1988) Anal. Biochem. 169:1-25.
Eisenach, Kathleen Davis, (1987) Ph.D. Dissertation Entitled "The Development of Moecular Probes for Mycobacterium Tuberculosis", abstract.

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