Mycelial pellets having a support core

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435171, 435174, 435178, 435179, 435254, 435288, C12P 706, C12P 102, C12N 1110, C12M 140

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active

044277750

ABSTRACT:
Spherical shaped mycelial pellets suitable for use in the biocatalytic conversion of organic compounds are prepared having a rigid spherical core surrounded by a porous webbed layer of structural integrity of a mycelial microorganism. The webbed layer is preferably separated from the core by a substantial void space and is attached to the core by a portion of the mycelium of the microorganism. The core may be composed of a cellulose derivative or agar. The pellets are prepared by forming a solution of a cellulose derivative or agar, mixing spores of a mycelial microorganism with the solution, precipitating the celluose derivative or agar to form beads containing the spores and incubating the beads in a culture medium.

REFERENCES:
patent: 4090022 (1978-05-01), Tsao et al.
patent: 4127447 (1978-11-01), Griffith et al.
patent: 4208482 (1980-06-01), Ehrenthal et al.
patent: 4321327 (1982-03-01), Chen et al.
Atkinson et al., The Completely Mixed Microbial Film Fermenter Trans. Instr. Chem. Engrs., vol. 50, 1972, (pp. 208-216).
Jack et al., The Immobilization of Whole Cells, Advances in Biochem. Eng., vol. 5 1977, (pp. 126-136 & 138-141).

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