Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1980-07-29
1981-11-10
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
260343, 424181, 424279, 435119, C07H 1708, C07D31300
Patent
active
042999537
ABSTRACT:
Mycarosyltylactone (5-O-mycarosyl-20-dihydro-20,23-dideoxytylonolide) which has the formula: ##STR1## 3,4'-diacyl ester derivatives of mycarosyltylactone wherein each of said esters is an ester of a monocarboxylic acid or a hemi-ester of a dicarboxylic acid, each of 1 to 18 carbon atoms, and the corresponding 3-acyl ester derivatives of tylactone, are useful intermediates in the preparation of macrolide antibiotics. New methods for making tylactone and the 3-acyl ester derivatives of tylactone are provided.
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Hamill Robert L.
Wild Gene M.
Eli Lilly and Company
Fan Jane T.
Harrison Nancy J.
Jiles Henry R.
Whale Arthur R.
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