Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-07-02
2008-11-25
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023200, C530S380000
Reexamination Certificate
active
07455970
ABSTRACT:
The present invention relates to a method of identifying a subject predisposed to ischemic stroke. The method includes the step of identifying a mutation in the subject that reduces the release rate of tissue plasminogen activator.
REFERENCES:
patent: WO-97/07240 (1997-02-01), None
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Bulens et al., “Rentinoic acid induction of human tissue-type plasminogen activator gene expression via a direct repeat element (DR5) located at −7 kilobases,” J Biol Chem 270(13):7167-7175, 1995.
Benza, RL et al. (1998), J. Thrombosis Thrombolysis 5, 143-50.
Austin, H et al., (2002) Stroke 33, 2762-9.
Iacoviello L et al. (1995), Fibrinolysis 10 (Supple 2), 13-6.
Bang C-O et al. (2001), Cerebrovascular Disease 11, 294-9.
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Hamilton-Bruce Monica Anne
Jannes Jim
Koblar Simon
Adelaide Research & Innovation Pty Ltd
Birch & Stewart Kolasch & Birch, LLP
Kosson Rosanne
Prouty Rebecca E.
The Queen Elizabeth Hospital Research Foundation Inc.
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