Mutated netrin-4, fragments thereof and their use as medicines

Details Mutated netrin-4, fragments thereof and their use as medicines Mutated netrin-4, fragments thereof and their use as medicines

2011-08-16

2011-08-16

Harris, Alana M (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S320100, C435S325000, C514S001000, C514S001100, C514S019200, C514S019300, C514S021200, C536S001001, C536S018700, C536S022100, C536S023100, C536S023500

Reexamination Certificate

active

07999072

ABSTRACT:
Described is use of a netrin selected among netrin-4, mutated netrin-4, netrin-1, netrin G1 or netrin-3, or one of their fragments or a nucleotide sequence encoding one of the netrins or one of the fragments, or an anti-idiotypic antibody of one of the netrins or of one of the fragments, or of a Fab fragment of the anti-idiotypic antibodies, for preparing a medicine for preventing or treating tumoral or non-tumoral pathologies.

REFERENCES:
patent: 6218526 (2001-04-01), Swimmer et al.
patent: 7358351 (2008-04-01), St. Croix et al.
patent: 2003/0017157 (2003-01-01), St. Croix et al.
patent: 2003/0207347 (2003-11-01), Olson et al.
patent: 2006/0073182 (2006-04-01), Wong et al.
patent: 01/54723 (2001-08-01), None
patent: 01/64837 (2001-09-01), None
Koch M et al “A Novel Member of the Netrin Family, Beta-Netrin, Shares Homology With the Beta Chain of Laminin: Identification, Expression, and Functional Characterization” The Journal of Cell Biology, Rockefeller University Press, US vol. 151, No. 2, Oct. 16, 2000, pp. 221-234, XP002944911.

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