Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-05-06
2000-08-01
Spector, Lorraine
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
536 235, 536 231, 435 691, 4353201, 435325, 4352523, 43525411, C07K 14435, C12N 1511, C12N 510
Patent
active
060968656
ABSTRACT:
The present invention relates to mutants of the green fluorescent protein having improved fluorescent properties at 37.degree. C. The mutants provide for improved methods of monitoring gene expression, e.g., for use as cell markers or protein expression indicators in prokaryotic and, especially, eucaryotic systems where the standard physiological temperature is 37.degree. C.
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Amgen Inc.
Crandall Craig A.
Kaufman Claire M.
Levy Ron K.
Odre Steven M.
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