Mutants of bone morphogenetic proteins

Details Mutants of bone morphogenetic proteins Mutants of bone morphogenetic proteins

1993-12-07

1995-03-21

Draper, Garnette D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2351, 530350, 530399, C12N 1512, C12N 1518, A61K 3736

Patent

active

053996771

ABSTRACT:
DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed, The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.

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