Mutant vaccinia virus and process for production thereof

Details Mutant vaccinia virus and process for production thereof Mutant vaccinia virus and process for production thereof

1987-07-30

1991-02-12

Teskin, Robin L.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

424 89, 4352402, C12N 700, C12N 1500, A61K 3912

Patent

active

049923749

ABSTRACT:
An improved mutant vaccinia virus providing a pock and plaque size on RK13 cells that is approximately the same as those of the Lister original, having a proliferation potency on YTV cells that is approximately the same as that of the Lister original, and having a neurovirulence, assessed by a recovery of an intrabrain virus, that is lower than that of the Lister original; and a process for the production thereof.

REFERENCES:
Takahashi-Nishmaki, et al., J. Gen. Virol. 68:2705-2710 1987.
Shida, et al., J of Virology, 62:4474-4480, 1988.
Proc. of Nat'l Acad. Sci. U.S.A., vol. 82, May 1985, pp. 3365-3369.
Nature, vol. 317, Oct. 31, 1985, No. 67262.
Biol. Abstracts, vol. 83, 1987, No. 107689.
M. Sugimoto et al., Microbiol. Immunol. vol. 29(5), 421-428, 1985 S. Hashizume, Vaccinia Viruses as Vectors for Vaccin Antigens, 87-99, 1985.

Affiliated with

Also associated with

Rating

Mutant vaccinia virus and process for production thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mutant vaccinia virus and process for production thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mutant vaccinia virus and process for production thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-20220