Mutant-type bioluminescent protein, and process for producing th

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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435440, 435441, 435 691, 435 711, 435 712, 435 8, 530858, C12N 902

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active

060748591

ABSTRACT:
According to the present invention, there can be provided a bioluminescent protein, luciferase excellent in thermostability etc. and with high catalytic efficiency.

REFERENCES:
patent: 5229285 (1993-07-01), Kajiyama et al.
patent: 5843746 (1998-12-01), Tatsumi et al.
Kajiyama et al., Isolation and Characterization of Mutants of Firefly Luciferase Which Produce Different Colors of Light, Protein Engineering, 4 (6):691-693, 1991.
Wood et al., Bioluminescent Click Beetles Revisited, J. Biolumin. Chemilum. 4: 31-39, Jul. 1989.
De Wet et al., Cloning of Firefly Luciferase cDNA and the Expression of Active Luciferase in Escherichia coli, PNAS 82: 7870-7873, Dec. 1985.
Masuda et al. Cloning and Sequence Analysis of cDNA for Luciferase of a Japanese Firefly, Lucioloa cruciatea, Gene 77: 265-270, 1989.
Kajuyama et al., Purification and Characterization of Luciferases from Fireflies, Luciola Cruciata and Luciola lateralis, Biochim. Biophys. Acta. 1120:228-232, 1992.

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