Mutant receptors and their use in a nuclear receptor-based...

Details Mutant receptors and their use in a nuclear receptor-based... Mutant receptors and their use in a nuclear receptor-based...

2007-08-20

2011-12-13

Shafer, Shulamith H (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S858000

Reexamination Certificate

active

08076454

ABSTRACT:
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.

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