Mutant enterotoxin of E. coli

Details Mutant enterotoxin of E. coli Mutant enterotoxin of E. coli

1984-12-19

1988-08-02

Warden, Robert J.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

435 91, 435253, 435849, 424 92, 424 93, 935 22, 935 27, 935 56, 935 63, 935 64, 935 65, C12M 1500, C12P 1932, A61K 3902, A01N 6300

Patent

active

047613726

ABSTRACT:
A plasmid which comprises genes coding for an immunogenic, non-toxic, heat-labile enterotoxin and/or a non-toxic, heat-stable enterotoxin are disclosed. The E. coli containing this plasmid is also described. The E. coli or the plasmids may additionally contain a colonization factor. Methods for producing the plasmid and the E. coli containing the same are described. A live vaccine is prepared with the E. coli and is useful for vaccinating humans and animals against certain diarrheal diseases.

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