Mutant DNA encoding protein phosphatase 1 G-subunit

Details Mutant DNA encoding protein phosphatase 1 G-subunit Mutant DNA encoding protein phosphatase 1 G-subunit

1995-10-02

1998-11-24

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 4352523, 4353201, 435325, 435195, 536 231, 536 243, 530350, 935 22, 935 66, C12P 1934, C07H 2104, C12N 1509, C12Q 168

Patent

active

058404864

ABSTRACT:
The present invention relates to a mutant DNA sequence encoding protein phosphatase 1 G-subunit, wherein a mutation of G to T occurs in the position of codon 905 of the coding sequence, a method of detecting a mutation in the gene encoding protein phosphatase 1 G-subunit, as well as a diagnostic composition and a test kit for use in the method.

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Dent, P., et al., Nature, vol. 348, pp. 302-308 (1990).
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Tang, P.M., et al., Jour. Biol. Chem., vol. 266, No. 24, pp. 15782-15789 (1991).
Vaag, A., et al., J. Clin. Invest., vol. 89, pp. 782-788 (1992).
Schalin-Jantti, C., et al., Diabetes, vol. 41, pp. 598-604 (1992).
Hubbard, M.J., et al., TIBS 18, pp. 172-177 (1993).

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