Mutant cells with altered sialic acid

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S325000, C435S440000, C424S093210, C424S093700

Reexamination Certificate

active

10081170

ABSTRACT:
The invention provides cells useful to propagate influenza virus mutants having reduced sialidase activity.

REFERENCES:
patent: 2004/0132164 (2004-07-01), Doyle et al.
patent: 407203958 (1995-08-01), None
Martin et al. Virology 241: 101-111, 1998.
Brandli et al, J. Biol. Chem. 263: 16283-16290, 1988.
Ito et al. J. Virol. 71:3357-3362, 1997.
Matta et al. Parasitol. Res. 85: 293-299, 1999.
Takeda et al. Mol. Biol. Cell. 11: 3219-3232, Sep. 2000.
Hughes, M. T., et al., “Adaptation of Influenza A Viruses to Cells Expressing Low Levels of Sialic Acid Leads to Loss of Neuraminidase Activity”,Journal of Virology, 75, (Apr. 2001), 3766-3770.
Hughes, M. T., et al., “Influenza A Viruses Lacking Sialidase Activity Can Undergo Multiple Cycles of Replication in Cell Culture, Eggs, or Mice”,Journal of Virology, 74, (Jun. 2000), 5206-5212.
Liu, Chongguang, et al., “Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding.”,Journal of Virology, 69(2), (Feb. 1995), 1099-106.
Liu, Chongguang, et al., “Selection and characterization of a neuraminidase-minus mutant of influenza virus and its rescue by cloned neuraminidase genes.”,Virology, 194(1), (1993), 403-407.
Masuda, H., et al., “Sustitution of Amino Acid Residue in Influenza A Virus Hemagglutinin Affects Recognition of Sialyl-Oligosaccharides Containing N-Glycolylneuraminic Acid”,FEBS Letters, 464, (1999), 71-74.
Neumann, G., et al., “Generation of Influenza A Viruses Entirely from Cloned cDNAs”,Proc. Natl. Acad. Sci. USA, 96, (Aug. 1999), 9345-9350.
Ray, Manas K., et al., “A novel glycosylation phenotype expressed by Lec23, a Chinese hamster ovary mutant deficient in alpha-glucosidase I.”,Journal of Biological Chemistry, 266(34); (Dec. 1991), 22818-22825.
Schultz-Cherry, S., et al., “Influenza Virus NS1 Protein Induces Apoptosis in Cultured Cells”,Journal of Virology, 75, (Sep. 2001), 7875-7881.
Yang, Ping, et al., “Hemagglutinin specificity and neuraminidase coding capacity of neuraminidase-deficient influenza viruses.”,Virology, 229(1), (1997), 155-165.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Mutant cells with altered sialic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mutant cells with altered sialic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mutant cells with altered sialic acid will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3837533

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.