Mutant Actinosynnema pretiosum strain with increased...

Details Mutant Actinosynnema pretiosum strain with increased... Mutant Actinosynnema pretiosum strain with increased...

2007-03-20

2007-03-20

Lilling, Herbert J. (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

C435S118000, C435S252100, C435S253200, C540S460000, C540S462000

Reexamination Certificate

active

10898169

ABSTRACT:
A microorganism that is a mutant bacterial strain of the speciesActinosynnema pretiosum, designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and capable of growth under varied culture conditions, and methods of producing maytansinoid ansamitocins by culturing PF4-4 in a suitable growth medium.

REFERENCES:
patent: 4331598 (1982-05-01), Hasegawa et al.
patent: 4450234 (1984-05-01), Hasegawa et al.
patent: 6573074 (2003-06-01), Fulston et al.
patent: 6790954 (2004-09-01), Chung et al.
patent: 2002/0015984 (2002-02-01), Fulston et al.
patent: 2003/0157694 (2003-08-01), Chung et al.
patent: WO 01/77360 (2001-10-01), None

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