Mutant 6-phosphogluconate dehydrogenase

Details Mutant 6-phosphogluconate dehydrogenase Mutant 6-phosphogluconate dehydrogenase

Filed on

2011-08-02

Date issued

2011-08-02

Examiner

Pak, Yong (Department: 1652)

Patent Class

Chemistry: molecular biology and microbiology

SubClass

Enzyme , proenzyme; compositions thereof; process for...

SubSubClass

Oxidoreductase

Other Related Categories

C435S440000, C435S106000, C435S069100, C435S071100, C435S252300, C435S320100, C435S004000, C435S006120, C536S023200

Type

Reexamination Certificate

Status

active

Patent number

07989191

Description

ABSTRACT:
The present invention relates to a polypeptide having a modified amino acid sequence of 6-phosphogluconate dehydrogenase (hereinafter abbreviated as GND) derived from a microorganism belonging to the genusCorynebacterium, said modification being substitution of the amino acid residue(s) at the position(s) corresponding to the 158th and/or the 361st amino acid(s) of the amino acid sequence shown in SEQ ID NO: 1, and having GND activity; DNA encoding the polypeptide; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a microorganism carrying the DNA on the chromosome; and a process for producing a useful substance which comprises culturing the transformant or the microorganism in a medium.

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