Mussel bioadhesive

Details Mussel bioadhesive Mussel bioadhesive

2005-03-25

2009-11-24

Tsang, Cecilia (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

C530S300000, C530S325000

Reexamination Certificate

active

07622550

ABSTRACT:
The present invention relates to a bioadhesive derived from mussel. In particular, it relates to a novelMytilus galloprovincialisfoot protein type 5 (MGFP-5) and a recombinant protein that is a hybrid of MGFP-5 and foot protein type 1 (FP-1), where an adhesive protein with adhesive activity can be economically mass-produced to be used in place of chemical adhesives through the present invention.

REFERENCES:
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patent: 2003/0065060 (2003-04-01), Qvist et al.
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GenBank Accession No. ABM97415, pp. 1-2. Accessed Feb. 24, 2009.
GenBank Accession No. AAX23972, pp. 1-2. Accessed Feb. 24, 2009.
GenBank Accession No. AAX23969, pp. 1-2. Accessed Feb. 24, 2009.
GenBank Accession No. CAA35954, pp. 1-2. Accessed Feb. 24, 2009.
GenBank Accession No. AAA98797, pp. 1-3. Accessed Feb. 24, 2009.
NCBI Accession No. AAS00463, Feb. 1, 2004.
Deming, T.J, “Mussel Byssus and biomolecular materials”, Current Opinion in Chemical Biology (1999), 3: 100-105.
Database GenPept [Online] Jan. 24, 2007, “Adhesive Plaque Protein”, BAA09851, retrieved from NCBI Sequence Viewer.
Database GenePept [Online] Jan. 24, 2003, “Adhesive Plaque Matrix Protein”, BAA09850, retrieved from NCBI Sequence Viewer.
Hwang et al., “Cloning and expression of novel mussel adhesive protein fromMytilus galloprovincialis”, Biomolecular Engineering (2003), 20(2):79.
Database Geneseq [Online] May 9, 2001, “Repetitive protein polymer protein sequence #76”, XP002432105 retrieved from EBI accession No. GSN. AAB72776.
Database UniProt [Online] Mar. 1, 2002, “Polyphenolic phosphoprotein mefp-5 precursor”, XP002432106 retrieved from EBI accession No. UNIPROT: Q8WTE8.
Database Geneseq [Online] Sep. 26, 2001, “Mussel adhesive derived peptide #2”, XP002432107 retrieved from EBI accession No. GSN:AAG65052.
Database Geneseq [Online] Oct. 21, 2002, “Glue protein repeat unit”, XP002432108 retrieved from EBI accession No. GSN: ABG69216.
Database Geneseq [Online] Sep. 9, 2004, “Mgfp-5 amino acid sequence, seq id 4”, XP002432109 retrieved from EBI accession No. GSP: ADQ78274.
Waite et al., “Polyphosphoprotein from the adhesive pads ofMytilus edulis”, Biochemistry (2001), 40(9):2887-2893.
Hwang et al., “Expression of functional recombinant mussel adhesive protein Mgfp-5 inEscherichia coli”, Applied and Environmental Microbiology (2004), 70(6):3352-3359.

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