Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Muscle
Reexamination Certificate
2006-11-07
2006-11-07
Wax, Robert A. (Department: 1653)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Muscle
C424S423000, C424S548000, C514S012200
Reexamination Certificate
active
07131994
ABSTRACT:
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
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Journal of Bone and Mineral Research, Apr. 2003, vol. 18, No. 4, p. 705, “In Vitro and In Vivo Synergistic Interactions Between the Runx2/Cbfa1 Transcription Factor and Bone Morphogenetic Protein-2 in Stimulating Osteoblast Differentiation”, Shuying Yang, Daoyan Wei, Dian Wang, Mattabhorn Phimphilai, Paul H. Krebsbach and Renny T. Franceschi.
Djurhuus M S et al.: “Methodological aspects of measuring human skeletal muscle electrolyte content and ouabain binding capacity.” Analytical Biochemistry. Jul. 1, 1998, vol. 260, No. 2., Jul. 1, 1998, pp. 218-222, XP002296843 ISSN: 0003-2697.
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Bianchi John R.
Cheung David T.
Howell, Jr. John W.
Mills C. Randal
Nataraj Chandrasekaran
Kosson Rosanne
McAndrews Held & Malloy
Pochopien Donald J.
Regeneration Technologies, Inc.
Wax Robert A.
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