Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-04-07
1995-04-04
Tsang, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514256, 514269, 514272, 514336, 514340, 514342, 514349, 514352, 514354, 514356, 514357, 544298, 544331, 544332, 544333, 544335, 546268, 546277, 546280, 546304, 546309, 546310, 546311, 546312, A61K 3144, A61K 31505, C07D23902, C07D21172
Patent
active
054038456
ABSTRACT:
Substituted 1,4,5,6 -tetrahydropyrimidine compositions, substituted 1,2,3,6 -tetrahydropyrimidine compositions and substituted 3,4,5,6 -tetrahydropyridine compositions are disclosed. They are useful for stimulating muscarinic receptors including, for example, treating the symptoms of cognitive disorders, especially impaired memory, which are associated with decreased acetylcholine synthesis and cholinergic cell degeneration.
REFERENCES:
patent: 4710508 (1987-12-01), Bergmeier et al.
patent: 4786648 (1988-11-01), Bergmeier et al.
Chemical Abstract 53:5276E (1958).
Chemical Abst. 89:109351d (1978).
Proceedings of the British Pharmacological Society, 1970, pp. 191-192.
Chem. Abstract 103:3305J (1984).
Chem. Abstract 83:178745y (1975).
J. Med. Chem. 1990, 33, 2690-2697.
J. Med. Chem. 1991, 34, 1086-1094.
Br. J. Pharmac. 1969, 37, 425-435.
Synthesis, Jul. 1975, pp. 426-427.
J. Org. Chem. vol. 38, No. 8, 1973.
J. Med. Chem. 1990, 33, 1128-1138.
J. Med. Chem. 1991, 34, 687-692.
J. Med. Chem. 1990, 33:2052-2059.
European Journal of Pharmacology 134(1987) 61-67.
Dunbar Philip G.
Durant Graham J.
Hoss Wayne P.
Messer, Jr. William S.
Tsang Cecilia
University of Toledo
LandOfFree
Muscarinic agonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Muscarinic agonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Muscarinic agonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2380871