Muscarine antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514304, 514316, 514317, 514318, 514323, 544333, 546125, 546126, 546186, 546187, C07D21114, C07D23526, C07D23926, A61K 31415

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active

057565082

ABSTRACT:
This invention is concerned with novel olones, derivatives thereof, their preparation, method of use and pharmaceutical compositions. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).

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O. Cervinka and P. Malon, Chem. Commun., 42, pp (1977).
D. L. Commins and J. D. Brown, Tetra Ltrs., 27(38), pp. 4549-4552 (1986).

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