Mus dunni endogenous retroviral packaging cell lines

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435355, C12N 510

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06136598&

ABSTRACT:
Retroviral packaging cells produce replication-defective retroviral particles capable of binding to Mus dunni endogenous virus retroviral receptors on target cells and are useful in gene transfer and gene therapy. The packaging cell employs a vector encoding a M. dunni retroviral Env protein and produces the retroviral particles at high titer.

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