Murine UCP3 polypeptides

Details Murine UCP3 polypeptides Murine UCP3 polypeptides

1998-10-14

1999-09-14

McKelvey, Terry

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C07K 1447

Patent

active

059524693

ABSTRACT:
The invention provides methods and compositions relating to a novel family of UCP3 polypeptides and related nucleic acids involved in metabolic regulation. The polypeptides may be produced recombinantly from transformed host cells from the disclosed mUCP3 encoding nucleic acids or purified from mammalian cells. The invention provides isolated mUCP3 hybridization probes, knock-out/in constructs and primers capable of specifically hybridizing with the disclosed mUCP3 genes, mUCP3-specific binding agents such as specific antibodies, animals and cells modified with the subject mUCP3 nucleic acids, and methods of making and using the subject compositions in the biopharmaceutical industry.

REFERENCES:
Ngo et al, The Protein Folding Problem and Tertiary Structure Prediction, Mertz et al (eds.), pp. 433 and 492-495, Birkhauser, Boston, 1994.

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