Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-06-30
1999-07-20
Ulm, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 6, 435 72, 435365, C12N 510
Patent
active
059255285
ABSTRACT:
The present invention thus relates to novel newt aFGF cDNA and sequence, newt FGFR1 cDNA and sequence, newt FGFR2 cDNA and sequence, newt FGFR3 cDNA and sequence, newt KGFR cDNA and sequence, and CHO-K1 cell line (KPTr2--2) expressing newt KGFR. Mutant cell lines (Tr31-5-1 and Tr33-1-2) that become non-responsive to aFGF stimulation are used to differentiate biological activities among different forms of aFGF and other FGF proteins. These novel sequences and cell lines substantially enhance the availability of newt acidic fibroblast growth factor and are useful for producing compositions for promoting growth and/or wound healing
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Ohio State University Research Foundation
Ulm John
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