Murine and human box-dependent myc-interacting protein (Bin1) an

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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530300, 530350, 5303871, 5303872, 5303873, 5303877, 5303879, 5303881, 53038815, 5303891, 536 231, 436501, C07K 1600, C07K 1642, G01N 3353

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06048702&

ABSTRACT:
The present invention provides antibodies raised against a Box-dependent myc-interacting polypeptide termed Bin1 or fragments thereof are provided. Also provided are compositions and methods utilizing these antibodies in the diagnosis and treatment of cancers and hyperplastic disease states. Further provided are oligonucleotides derived from sequences encoding Bin1, as well as compositions and methods utilizing same for diagnostic and therapeutic purposes.

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