Murf gene and enzyme of Pseudomonas aeruginosa

Details Murf gene and enzyme of Pseudomonas aeruginosa Murf gene and enzyme of Pseudomonas aeruginosa

2005-09-27

2005-09-27

Kerr, Kathleen (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S183000, C435S320100, C435S252300, C435S254110, C435S419000, C435S325000, C536S023100, C536S023200, C536S023700

Reexamination Certificate

active

06949336

ABSTRACT:
This invention provides isolated polynucleotides that encode the MurF (UDP-N-acetylmuramyl-L-alanine-D-glutamate-m-DaD:D-alanine-D-alanine ligase) protein ofPseudomonas aeruginosa. Purified and isolated MurF recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurF proteins are described. Assays for the identification of modulators of the expression of murF and inhibitors of the activity of MurF, are also provided.

REFERENCES:
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