MurE protein and gene of pseudomonas aeruginosa

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S069300, C435S320100

Reexamination Certificate

active

06870041

ABSTRACT:
This invention provides isolated polynucleotides that encode the MurE protein ofPseudomonas aeruginosa. Purified and isolated MurE recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurE proteins are described. Assays for the identification of modulators of the of expression of murE and inhibitors of the activity of MurE, are also provided.

REFERENCES:
patent: 6251647 (2001-06-01), de Lencastre et al.
patent: 6551795 (2003-04-01), Rubenfield et al.
Liao et al. timicrob. Agents Chemother. 39: 1971-1974, 1995.

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