Muramyldipeptide active ester derivatives

Details Muramyldipeptide active ester derivatives Muramyldipeptide active ester derivatives

1984-08-20

1987-07-21

Phillips, Delbert R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C08B 3700

Patent

active

046818561

ABSTRACT:
Muramyldipeptide active ester derivatives represented by the formula: ##STR1## wherein R.sub.1 represents a straight or branched chain fatty acid residue having 2 to 30 carbon atoms; R.sub.2 represents an active ester residue; and "Acyl" represents an acyl group having 2 to 6 carbon atoms. These compounds are applicable as haptens for the immunotherapy and exhibit antitumor activity.

REFERENCES:
Hamaoka et al., Chemical Abstracts, 103, 689 (1985), abst. No. 71711 p.
Kusumoto et al., Bulletin of the Chemical Society of Japan, 51(7), 2122-2126 (1978).

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