Muramyl peptides and processes for their manufacture

Details Muramyl peptides and processes for their manufacture Muramyl peptides and processes for their manufacture

1984-05-09

1985-10-22

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

525 5411, A61K 3700, C07D33332

Patent

active

045489238

ABSTRACT:
The compounds of the formula I ##STR1## in which each of R.sup.1, R.sup.4 and R.sup.6, independently of the others, represents hydrogen or lower alkanoyl, R.sup.2 represents C.sub.1-4 -alkyl, hydroxymethyl or phenyl, R.sup.3 represents hydrogen or methyl, R.sup.5 represents hydrogen or C.sub.1-3 -alkyl, R.sup.7 represents C.sub.1-3 -alkyl that is unsubstituted or substituted by hydroxy, mercapto or methylthio, R.sup.8 represents hydrogen or lower alkyl, X represents oxygen or the group NH, Y represents C.sub.1-4 -alkylidene, and each of R.sup.9 and R.sup.10, independently of the other, represents C.sub.11-17 -alkyl or C.sub.11-17 -alkenyl, and their salts, have an immunostimulating activeity.

REFERENCES:
patent: 4323560 (1982-04-01), Baschang et al.
patent: 4414204 (1983-11-01), Tarcsay et al.
U.S. application 283,759.
U.S. application 340,680.

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