Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1982-01-06
1984-01-24
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3700, C07C10352
Patent
active
044276591
ABSTRACT:
The invention relates to novel compounds of the muramyl-peptide type and to their uses. The muramyl-peptides according to the invention comprise at least two aminoacyl residues in the peptide chain, the second of these aminoacyl residues being D-glutamyl, and they are characterized in that the nitrogen of the first amino-acyl, and forming part of the pepetide linkage connecting the muramyl group to the peptide residue, is substituted by an alkyl group. These compounds are useful notably for the preparation of pharmaceutical compositions, in particular by reason of their regulatory properties on the immune responses of the organism.
REFERENCES:
patent: 4082735 (1978-04-01), Jones et al.
patent: 4082736 (1978-04-01), Jones et al.
patent: 4094971 (1978-06-01), Chedid et al.
patent: 4101536 (1978-07-01), Yamamura et al.
patent: 4101649 (1978-07-01), Adam et al.
patent: 4185089 (1980-01-01), Derrien et al.
R. R. Acad. SC. Paris, t.284 (Jan. 31, 1977) 405-408.
Proc. NatAcad. Sci. 73, 1976, 2472-2475.
Biochem. and Biophys. Res. Commun. 66, 1975, 1316-1322.
Biochem. and Biophys. Res. Commun. 72, 1976, 339-346.
Symposium Internatl. les Immunostimulants Bacteriens (Structures Chimiques, Mecanismes d?3 Action Applications) Paris, Institut Pasteur Oct. 14, 1974 Resumes' de Communication Abstract.
Biken Journal, vol. 18, 105-111 (1975).
Audibert Francoise
Chedid Louis
Choay Jean
Le Francier Pierre
Lederer Edgar
Agence Nationale de Valorisation de la Recherche (ANVAR)
Phillips Delbert R.
LandOfFree
Muramyl peptide substituted on a peptide nitrogen and medicament does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Muramyl peptide substituted on a peptide nitrogen and medicament, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Muramyl peptide substituted on a peptide nitrogen and medicament will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1287049