Multivalent pneumococcal vaccine and preparation thereof

Details Multivalent pneumococcal vaccine and preparation thereof Multivalent pneumococcal vaccine and preparation thereof

1984-04-12

1987-08-11

Kight, John

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 514 54, 536 11, 536123, 536127, A61K 39116

Patent

active

046861025

ABSTRACT:
A multivalent pneumococcal vaccine consisting of immunogenic amounts of purified pneumococcal capsular polysaccharide (substantially absent "C" polysaccharide) of pneumococcal types (Danish designation) 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F and 33F, and from none to one or both of 6A and 25, and combinations thereof and methods of purifying pneumococcal capsular polysaccharide types 3, 5, 9V, 10A, 11A, 15B, 17F, 19A, 22F and 33F.

REFERENCES:
patent: 4242501 (1980-12-01), Cano et al.
Bargono et al., "Vaccination and Revaccination with Polyvalent . . . Infant", Proc. for Soc. of Exp. Biol. and Med. 157, 1978, pp. 148-154.
Smit et al., Abst. #39335.
Hellerman et al., Abst. #28387.
Cowan et al., Abst. #20714x.
Robbins et al., Consideration for Formulating the Second-Generation Pneumococcal Capsular Polysaccaride Vaccine . . . Groups, J. Infect. Dis., 148(6), 1983, p. 1136.
Douglas et al., Antibody Response to Pneumococcal Vaccination . . . Age, J. Inf. Disease, 148(1), 1983, p. 131.
C.A. vol. 90, #20714x, Pneumococcal Polysaccharide Immunization . . . Children, Cowan et al.
Abst. Howie et al., Use of Pneumococcal Polysaccharide Vaccine . . . Gp . . . Pediatrics, 73(c), 1984, pp. 79-81.
Abst. Hansman, Sereotypes in Pneumococcal Disease . . . 1978, Aust. N. Z. J. Med. 13(4), 1983, p. 359.
Abst. Gerichter et al., Survey of Pneumococcal Types in Israel, Irs. J. Med. Sci., 19(6), 1983, pp. 520-523.
Abst. De Bac et al., A Multicentric Study for Serotypes . . . Holy, Ric. Clin. Lab., 11(2), 1981, pp. 145-150.

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