Multivalent inhibitors of serum amyloid P component

Details Multivalent inhibitors of serum amyloid P component Multivalent inhibitors of serum amyloid P component

2004-05-12

2009-06-30

Lewis, Patrick T (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S002600, C514S023000, C514S024000

Reexamination Certificate

active

07553819

ABSTRACT:
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such, the compounds of the invention are useful for treating amyloidosis and diseases associated with amyloidosis, for example Alzheimer&supl;s disease and maturity onset diabetes mellitus.

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